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Structural basis of myelin-associated glycoprotein adhesion and signalling

Myelin-associated glycoprotein (MAG) is a myelin-expressed cell-adhesion and bi-directional signalling molecule. MAG maintains the myelin–axon spacing by interacting with specific neuronal glycolipids (gangliosides), inhibits axon regeneration and controls myelin formation. The mechanisms underlying...

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Detalles Bibliográficos
Autores principales: Pronker, Matti F., Lemstra, Suzanne, Snijder, Joost, Heck, Albert J. R., Thies-Weesie, Dominique M. E., Pasterkamp, R. Jeroen, Janssen, Bert J. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5150538/
https://www.ncbi.nlm.nih.gov/pubmed/27922006
http://dx.doi.org/10.1038/ncomms13584