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Reactivity of disulfide bonds is markedly affected by structure and environment: implications for protein modification and stability
Disulfide bonds play a key role in stabilizing protein structures, with disruption strongly associated with loss of protein function and activity. Previous data have suggested that disulfides show only modest reactivity with oxidants. In the current study, we report kinetic data indicating that sele...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5150571/ https://www.ncbi.nlm.nih.gov/pubmed/27941824 http://dx.doi.org/10.1038/srep38572 |