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In vitro effects of the small-molecule protein kinase C agonists on HIV latency reactivation

The persistence of latently HIV-infected cellular reservoirs represents the major obstacle to virus eradication in patients under antiretroviral therapy (ART). Cure strategies to eliminate these reservoirs are thus needed to reactivate proviral gene expression in latently infected cells. In this stu...

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Detalles Bibliográficos
Autores principales: Brogdon, Jessica, Ziani, Widade, Wang, Xiaolei, Veazey, Ronald S., Xu, Huanbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5150635/
https://www.ncbi.nlm.nih.gov/pubmed/27941949
http://dx.doi.org/10.1038/srep39032