ASIC1a regulates insular long-term depression and is required for the extinction of conditioned taste aversion

Acid-sensing ion channel 1a (ASIC1a) has been shown to play important roles in synaptic plasticity, learning and memory. Here we identify a crucial role for ASIC1a in long-term depression (LTD) at mouse insular synapses. Genetic ablation and pharmacological inhibition of ASIC1a reduced the induction...

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Detalles Bibliográficos
Autores principales: Li, Wei-Guang, Liu, Ming-Gang, Deng, Shining, Liu, Yan-Mei, Shang, Lin, Ding, Jing, Hsu, Tsan-Ting, Jiang, Qin, Li, Ying, Li, Fei, Zhu, Michael Xi, Xu, Tian-Le
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5150990/
https://www.ncbi.nlm.nih.gov/pubmed/27924869
http://dx.doi.org/10.1038/ncomms13770

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5150990/
https://www.ncbi.nlm.nih.gov/pubmed/27924869
http://dx.doi.org/10.1038/ncomms13770

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