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HPLC estimation of iothalamate to measure glomerular filtration rate in humans

Glomerular filtration rate (GFR) is usually determined by estimation of iothalamate (IOT) clearance. We have developed and validated an accurate and robust method for the analysis of IOT in human plasma and urine. The mobile phase consisted of methanol and 50 mM sodium phosphate (10:90; v/v). Flow r...

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Detalles Bibliográficos
Autores principales: Shah, Iltaf, Barker, James, Naughton, Declan P., Barton, Stephen J., Ashraf, Syed Salman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5151096/
https://www.ncbi.nlm.nih.gov/pubmed/28028385
http://dx.doi.org/10.1186/s13065-016-0227-3