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The effect of polymer and CaCl(2) concentrations on the sulfasalazine release from alginate-N,O-carboxymethyl chitosan beads
In this study, pH-sensitive blended polymeric beads were prepared by ionic gelation of mixed alginate and N,O-carboxymethyl chitosan (NOCC) solutions in aqueous media containing calcium chloride. To prepare drug-loaded beads, sulfasalazine (SA) as a model drug was added to the initial aqueous polyme...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5151116/ https://www.ncbi.nlm.nih.gov/pubmed/29470666 http://dx.doi.org/10.1186/2194-0517-2-10 |