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The effect of polymer and CaCl(2) concentrations on the sulfasalazine release from alginate-N,O-carboxymethyl chitosan beads

In this study, pH-sensitive blended polymeric beads were prepared by ionic gelation of mixed alginate and N,O-carboxymethyl chitosan (NOCC) solutions in aqueous media containing calcium chloride. To prepare drug-loaded beads, sulfasalazine (SA) as a model drug was added to the initial aqueous polyme...

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Detalles Bibliográficos
Autores principales: Tavakol, Moslem, Vasheghani-Farahani, Ebrahim, Hashemi-Najafabadi, Sameereh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5151116/
https://www.ncbi.nlm.nih.gov/pubmed/29470666
http://dx.doi.org/10.1186/2194-0517-2-10