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Free Fatty Acids Modulate Thrombin Mediated Fibrin Generation Resulting in Less Stable Clots

Upon platelet activation, free fatty acids are released at the stage of thrombus formation, but their effects on fibrin formation are largely unexplored. Our objective was to characterize the kinetic effects of fatty acids on thrombin activity, as well as the structural and mechanical properties of...

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Detalles Bibliográficos
Autores principales: Tanka-Salamon, Anna, Komorowicz, Erzsébet, Szabó, László, Tenekedjiev, Kiril, Kolev, Krasimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5152833/
https://www.ncbi.nlm.nih.gov/pubmed/27942000
http://dx.doi.org/10.1371/journal.pone.0167806