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Site-specific mutagenesis of Drosophila proliferating cell nuclear antigen enhances its effects on calf thymus DNA polymerase δ

BACKGROUND: We and others have shown four distinct and presumably related effects of mammalian proliferating cell nuclear antigen (PCNA) on DNA synthesis catalyzed by mammalian DNA polymerase δ(pol δ). In the presence of homologous PCNA, pol δ exhibits 1) increased absolute activity; 2) increased pr...

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Detalles Bibliográficos
Autores principales: Mozzherin, Dmitry Ju, McConnell, Maeve, Miller, Holly, Fisher, Paul A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC515284/
https://www.ncbi.nlm.nih.gov/pubmed/15310391
http://dx.doi.org/10.1186/1471-2091-5-13