A Trojan-Horse Peptide-Carboxymethyl-Cytidine Antibiotic from Bacillus amyloliquefaciens

[Image: see text] Microcin C and related antibiotics are Trojan-horse peptide-adenylates. The peptide part is responsible for facilitated transport inside the sensitive cell, where it gets processed to release a toxic warhead—a nonhydrolyzable aspartyl-adenylate, which inhibits aspartyl-tRNA synthet...

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Detalles Bibliográficos
Autores principales: Serebryakova, Marina, Tsibulskaya, Darya, Mokina, Olga, Kulikovsky, Alexey, Nautiyal, Manesh, Van Aerschot, Arthur, Severinov, Konstantin, Dubiley, Svetlana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2016
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5152938/
https://www.ncbi.nlm.nih.gov/pubmed/27934031
http://dx.doi.org/10.1021/jacs.6b09853

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5152938/
https://www.ncbi.nlm.nih.gov/pubmed/27934031
http://dx.doi.org/10.1021/jacs.6b09853

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