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A Trojan-Horse Peptide-Carboxymethyl-Cytidine Antibiotic from Bacillus amyloliquefaciens
[Image: see text] Microcin C and related antibiotics are Trojan-horse peptide-adenylates. The peptide part is responsible for facilitated transport inside the sensitive cell, where it gets processed to release a toxic warhead—a nonhydrolyzable aspartyl-adenylate, which inhibits aspartyl-tRNA synthet...
Autores principales: | Serebryakova, Marina, Tsibulskaya, Darya, Mokina, Olga, Kulikovsky, Alexey, Nautiyal, Manesh, Van Aerschot, Arthur, Severinov, Konstantin, Dubiley, Svetlana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2016
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5152938/ https://www.ncbi.nlm.nih.gov/pubmed/27934031 http://dx.doi.org/10.1021/jacs.6b09853 |
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