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Phosphorylated guanine nucleotide exchange factor C3G, induced by pervanadate and Src family kinases localizes to the Golgi and subcortical actin cytoskeleton

BACKGROUND: The guanine nucleotide exchange factor C3G (RapGEF1) along with its effector proteins participates in signaling pathways that regulate eukaryotic cell proliferation, adhesion, apoptosis and embryonic development. It activates Rap1, Rap2 and R-Ras members of the Ras family of GTPases. C3G...

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Detalles Bibliográficos
Autores principales: Radha, Vegesna, Rajanna, Ajumeera, Swarup, Ghanshyam
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC515295/
https://www.ncbi.nlm.nih.gov/pubmed/15320955
http://dx.doi.org/10.1186/1471-2121-5-31