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Opposite role of Bax and BCL-2 in the anti-tumoral responses of the immune system

BACKGROUND: The relative role of anti apoptotic (i.e. Bcl-2) or pro-apoptotic (e.g. Bax) proteins in tumor progression is still not completely understood. METHODS: The rat glioma cell line A15A5 was stably transfected with human Bcl-2 and Bax transgenes and the viability of theses cell lines was ana...

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Detalles Bibliográficos
Autores principales: Bougras, Gwenola, Cartron, Pierre-François, Gautier, Fabien, Martin, Stéphane, LeCabellec, Marité, Meflah, Khaled, Gregoire, Marc, Vallette, François M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC515305/
https://www.ncbi.nlm.nih.gov/pubmed/15331018
http://dx.doi.org/10.1186/1471-2407-4-54