Combination effects of sorafenib with PI3K inhibitors under hypoxia in colorectal cancer

AIM: This study reports the influence of hypoxia on response of colorectal cancer cells to anticancer effects of sorafenib in combination with PI3K inhibitors GDC-0941 and BEZ-235. MATERIALS AND METHODS: All hypoxic exposures were carried out at 1% O(2)/5% CO(2). Antiproliferation activity was evalu...

Descripción completa

Detalles Bibliográficos
Autores principales: Bhatia, Dimple R, Thiagarajan, Padma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5153268/
https://www.ncbi.nlm.nih.gov/pubmed/27995152
http://dx.doi.org/10.2147/HP.S115500

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5153268/
https://www.ncbi.nlm.nih.gov/pubmed/27995152
http://dx.doi.org/10.2147/HP.S115500

Ejemplares similares