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Attenuation of RANKL-induced Osteoclast Formation via p38-mediated NFATc1 Signaling Pathways by Extract of Euphorbia Lathyris L

BACKGROUND: Osteoclasts are the only cell type capable of breaking down bone matrix, and its excessive activation is responsible for the development of bone-destructive diseases. Euphorbia lathyris L. (ELL) is an herbal plant that belongs to the Euphorbiaceae family. This study investigated the effe...

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Detalles Bibliográficos
Autores principales: Kang, Ju-Hee, Lim, Hyojung, Jeong, Ji-Eun, Yim, Mijung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Bone and Mineral Research 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5153377/
https://www.ncbi.nlm.nih.gov/pubmed/27965942
http://dx.doi.org/10.11005/jbm.2016.23.4.207