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Activation of Sphingosine 1-Phosphate Receptor 1 Enhances Hippocampus Neurogenesis in a Rat Model of Traumatic Brain Injury: An Involvement of MEK/Erk Signaling Pathway

Among sphingosine 1-phosphate receptors (S1PRs) family, S1PR1 has been shown to be the most highly expressed subtype in neural stem cells (NSCs) and plays a crucial role in the migratory property of NSCs. Recent studies suggested that S1PR1 was expressed abundantly in the hippocampus, a specific neu...

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Detalles Bibliográficos
Autores principales: Ye, Yuqin, Zhao, Zhenyu, Xu, Hongyu, Zhang, Xin, Su, Xinhong, Yang, Yongxiang, Yu, Xinguang, He, Xiaosheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5153466/
https://www.ncbi.nlm.nih.gov/pubmed/28018679
http://dx.doi.org/10.1155/2016/8072156