The Significance of the Location of Mutations for the Native-State Dynamics of Human Lysozyme

The conversion of human lysozyme into amyloid fibrils is associated with a rare but fatal hereditary form of nonneuropathic systemic amyloidosis. The accumulation of large amounts of aggregated protein is thought to be initiated by the formation of transient intermediate species of disease-related l...

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Detalles Bibliográficos
Autores principales: Ahn, Minkoo, Hagan, Christine L., Bernardo-Gancedo, Ana, De Genst, Erwin, Newby, Francisco N., Christodoulou, John, Dhulesia, Anne, Dumoulin, Mireille, Robinson, Carol V., Dobson, Christopher M., Kumita, Janet R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2016
Materias:
Proteins
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5153563/
https://www.ncbi.nlm.nih.gov/pubmed/27926837
http://dx.doi.org/10.1016/j.bpj.2016.10.028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5153563/
https://www.ncbi.nlm.nih.gov/pubmed/27926837
http://dx.doi.org/10.1016/j.bpj.2016.10.028

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