Regional CAR-T cell infusions for peritoneal carcinomatosis are superior to systemic delivery

Metastatic spread of colorectal cancer (CRC) to the peritoneal cavity is common and difficult to treat, with many patients dying from malignant bowel obstruction. Chimeric antigen receptor T cell (CAR-T) immunotherapy has shown great promise, and we previously reported murine and phase I clinical st...

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Detalles Bibliográficos
Autores principales: Katz, Steven, Point, Gary R., Cunetta, Marissa, Thorn, Mitchell, Guha, Prajna, Espat, N. Joseph, Boutros, Cherif, Hanna, Nader, Junghans, Richard P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5153580/
https://www.ncbi.nlm.nih.gov/pubmed/27080226
http://dx.doi.org/10.1038/cgt.2016.14

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5153580/
https://www.ncbi.nlm.nih.gov/pubmed/27080226
http://dx.doi.org/10.1038/cgt.2016.14

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