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CircRNA accumulation in the aging mouse brain

Circular RNAs (circRNAs) are a newly appreciated class of RNAs expressed across diverse phyla. These enigmatic transcripts are most commonly generated by back-splicing events from exons of protein-coding genes. This results in highly stable RNAs due to the lack of free 5′ and 3′ ends. CircRNAs are e...

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Detalles Bibliográficos
Autores principales: Gruner, Hannah, Cortés-López, Mariela, Cooper, Daphne A., Bauer, Matthew, Miura, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5153657/
https://www.ncbi.nlm.nih.gov/pubmed/27958329
http://dx.doi.org/10.1038/srep38907