Cargando…

The curious case of an internal pilot in a multicentre randomised trial—time for a rethink?

Multicentre randomised trials are complex projects with many operational uncertainties. The embedding of a formal check upon study progress and viability at a pre-specified time point (sometimes referred to as an ‘internal pilot’) is becoming increasingly common within multicentre pragmatic randomis...

Descripción completa

Detalles Bibliográficos
Autores principales: Cook, Jonathan Alistair, Beard, David John, Cook, Johanna Rosemary, MacLennan, Graeme Stewart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5153752/
https://www.ncbi.nlm.nih.gov/pubmed/27965888
http://dx.doi.org/10.1186/s40814-016-0113-8