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The curious case of an internal pilot in a multicentre randomised trial—time for a rethink?
Multicentre randomised trials are complex projects with many operational uncertainties. The embedding of a formal check upon study progress and viability at a pre-specified time point (sometimes referred to as an ‘internal pilot’) is becoming increasingly common within multicentre pragmatic randomis...
Autores principales: | Cook, Jonathan Alistair, Beard, David John, Cook, Johanna Rosemary, MacLennan, Graeme Stewart |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5153752/ https://www.ncbi.nlm.nih.gov/pubmed/27965888 http://dx.doi.org/10.1186/s40814-016-0113-8 |
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