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Crystal Structure of Escherichia coli originated MCR-1, a phosphoethanolamine transferase for Colistin Resistance

MCR-1 is a phosphoethanolamine (pEtN) transferase that modifies the pEtN moiety of lipid A, conferring resistance to colistin, which is an antibiotic belonging to the class of polypeptide antibiotics known as polymyxins and is the last-line antibiotic used to treat multidrug resistant bacterial infe...

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Detalles Bibliográficos
Autores principales: Hu, Menglong, Guo, Jiubiao, Cheng, Qipeng, Yang, Zhiqiang, Chan, Edward Wai Chi, Chen, Sheng, Hao, Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5153839/
https://www.ncbi.nlm.nih.gov/pubmed/27958270
http://dx.doi.org/10.1038/srep38793