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Crystal Structure of Escherichia coli originated MCR-1, a phosphoethanolamine transferase for Colistin Resistance
MCR-1 is a phosphoethanolamine (pEtN) transferase that modifies the pEtN moiety of lipid A, conferring resistance to colistin, which is an antibiotic belonging to the class of polypeptide antibiotics known as polymyxins and is the last-line antibiotic used to treat multidrug resistant bacterial infe...
Autores principales: | Hu, Menglong, Guo, Jiubiao, Cheng, Qipeng, Yang, Zhiqiang, Chan, Edward Wai Chi, Chen, Sheng, Hao, Quan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5153839/ https://www.ncbi.nlm.nih.gov/pubmed/27958270 http://dx.doi.org/10.1038/srep38793 |
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