Exchanges of genomic domains between poliovirus and other cocirculating species C enteroviruses reveal a high degree of plasticity

The attenuated Sabin strains contained in the oral poliomyelitis vaccine are genetically unstable, and their circulation in poorly immunized populations can lead to the emergence of pathogenic circulating vaccine-derived polioviruses (cVDPVs). The recombinant nature of most cVDPV genomes and the pre...

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Detalles Bibliográficos
Autores principales: Bessaud, Maël, Joffret, Marie-Line, Blondel, Bruno, Delpeyroux, Francis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5153852/
https://www.ncbi.nlm.nih.gov/pubmed/27958320
http://dx.doi.org/10.1038/srep38831

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5153852/
https://www.ncbi.nlm.nih.gov/pubmed/27958320
http://dx.doi.org/10.1038/srep38831

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