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Exchanges of genomic domains between poliovirus and other cocirculating species C enteroviruses reveal a high degree of plasticity
The attenuated Sabin strains contained in the oral poliomyelitis vaccine are genetically unstable, and their circulation in poorly immunized populations can lead to the emergence of pathogenic circulating vaccine-derived polioviruses (cVDPVs). The recombinant nature of most cVDPV genomes and the pre...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5153852/ https://www.ncbi.nlm.nih.gov/pubmed/27958320 http://dx.doi.org/10.1038/srep38831 |