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Adelmidrol, in combination with hyaluronic acid, displays increased anti-inflammatory and analgesic effects against monosodium iodoacetate-induced osteoarthritis in rats

BACKGROUND: Osteoarthritis (OA) is a degenerative joint disease produced by a cascade of events that can ultimately lead to joint damage. The aim of this study was to evaluate the effect of adelmidrol, a synthetic palmitoylethanolamide analogue, combined with hyaluronic acid on pain severity and mod...

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Detalles Bibliográficos
Autores principales: Di Paola, Rosanna, Fusco, Roberta, Impellizzeri, Daniela, Cordaro, Marika, Britti, Domenico, Morittu, Valeria Maria, Evangelista, Maurizio, Cuzzocrea, Salvatore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5153857/
https://www.ncbi.nlm.nih.gov/pubmed/27955699
http://dx.doi.org/10.1186/s13075-016-1189-5