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Post-mortem histopathology underlying β-amyloid PET imaging following flutemetamol F 18 injection

In vivo imaging of fibrillar β-amyloid deposits may assist clinical diagnosis of Alzheimer’s disease (AD), aid treatment selection for patients, assist clinical trials of therapeutic drugs through subject selection, and be used as an outcome measure. A recent phase III trial of [(18)F]flutemetamol p...

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Detalles Bibliográficos
Autores principales: Ikonomovic, Milos D., Buckley, Chris J., Heurling, Kerstin, Sherwin, Paul, Jones, Paul A., Zanette, Michelle, Mathis, Chester A., Klunk, William E., Chakrabarty, Aruna, Ironside, James, Ismail, Azzam, Smith, Colin, Thal, Dietmar R., Beach, Thomas G., Farrar, Gill, Smith, Adrian P. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154022/
https://www.ncbi.nlm.nih.gov/pubmed/27955679
http://dx.doi.org/10.1186/s40478-016-0399-z