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The magnitude and temporal changes of response in the placebo arm of surgical randomized controlled trials: a systematic review and meta-analysis

BACKGROUND: Understanding changes in the placebo arm is essential for correct design and interpretation of randomized controlled trials (RCTs). It is assumed that placebo response, defined as the total improvement in the placebo arm of surgical trials, is large; however, its precise magnitude and pr...

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Detalles Bibliográficos
Autores principales: Wartolowska, Karolina A., Feakins, Benjamin G., Collins, Gary S., Cook, Jonathan, Judge, Andrew, Rombach, Ines, Dean, Benjamin J. F., Smith, James A., Carr, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154040/
https://www.ncbi.nlm.nih.gov/pubmed/27955685
http://dx.doi.org/10.1186/s13063-016-1720-7