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Planar cell polarity genes Frizzled3a, Vangl2, and Scribble are required for spinal commissural axon guidance

BACKGROUND: A fundamental feature of early nervous system development is the guidance of axonal projections to their targets in order to assemble neural circuits that control behavior. Spinal commissural neurons are an attractive model to investigate the multiple guidance cues that control growth co...

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Detalles Bibliográficos
Autores principales: Sun, Simon D., Purdy, Ashley M., Walsh, Gregory S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154073/
https://www.ncbi.nlm.nih.gov/pubmed/27955617
http://dx.doi.org/10.1186/s12868-016-0318-z