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Immunohistochemical and in situ hybridization study of urate transporters GLUT9/URATv1, ABCG2, and URAT1 in the murine brain

BACKGROUND: Uric acid (UA) is known to exert neuroprotective effects in the brain. However, the mechanism of UA regulation in the brain is not well characterized. In our previous study, we described that the mouse urate transporter URAT1 is localized to the cilia and apical surface of ventricular ep...

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Detalles Bibliográficos
Autores principales: Tomioka, Naoko H., Tamura, Yoshifuru, Takada, Tappei, Shibata, Shigeru, Suzuki, Hiroshi, Uchida, Shunya, Hosoyamada, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154092/
https://www.ncbi.nlm.nih.gov/pubmed/27955673
http://dx.doi.org/10.1186/s12987-016-0046-x