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β-Amyloid triggers aberrant over-scaling of homeostatic synaptic plasticity

The over-production of β-amyloid (Aβ) has been strongly correlated to neuronal dysfunction and altered synaptic plasticity in Alzheimer’s disease (AD). Accordingly, it has been proposed that disrupted synaptic transmission and neuronal network instability underlie memory failure that is evident in t...

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Detalles Bibliográficos
Autores principales: Gilbert, James, Shu, Shu, Yang, Xin, Lu, Youming, Zhu, Ling-Qiang, Man, Heng-Ye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154098/
https://www.ncbi.nlm.nih.gov/pubmed/27955702
http://dx.doi.org/10.1186/s40478-016-0398-0