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Using re-randomization to increase the recruitment rate in clinical trials – an assessment of three clinical areas

BACKGROUND: Patient recruitment in clinical trials is often challenging, and as a result, many trials are stopped early due to insufficient recruitment. The re-randomization design allows patients to be re-enrolled and re-randomized for each new treatment episode that they experience. Because it all...

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Detalles Bibliográficos
Autor principal: Kahan, Brennan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154140/
https://www.ncbi.nlm.nih.gov/pubmed/27964743
http://dx.doi.org/10.1186/s13063-016-1736-z