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A primer on the use of mouse models for identifying direct sex chromosome effects that cause sex differences in non-gonadal tissues
In animals with heteromorphic sex chromosomes, all sex differences originate from the sex chromosomes, which are the only factors that are consistently different in male and female zygotes. In mammals, the imbalance in Y gene expression, specifically the presence vs. absence of Sry, initiates the di...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154145/ https://www.ncbi.nlm.nih.gov/pubmed/27999654 http://dx.doi.org/10.1186/s13293-016-0115-5 |