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A primer on the use of mouse models for identifying direct sex chromosome effects that cause sex differences in non-gonadal tissues

In animals with heteromorphic sex chromosomes, all sex differences originate from the sex chromosomes, which are the only factors that are consistently different in male and female zygotes. In mammals, the imbalance in Y gene expression, specifically the presence vs. absence of Sry, initiates the di...

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Detalles Bibliográficos
Autores principales: Burgoyne, Paul S., Arnold, Arthur P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154145/
https://www.ncbi.nlm.nih.gov/pubmed/27999654
http://dx.doi.org/10.1186/s13293-016-0115-5