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LW-AFC, a new formula derived from Liuwei Dihuang decoction, ameliorates behavioral and pathological deterioration via modulating the neuroendocrine-immune system in PrP-hAβPPswe/PS1(ΔE9) transgenic mice

BACKGROUND: Accumulating evidence implicates the neuroendocrine immunomodulation (NIM) network in the physiopathological mechanism of Alzheimer’s disease (AD). Notably, we previously revealed that the NIM network is dysregulated in the PrP-hAβPPswe/PS1(ΔE9) (APP/PS1) transgenic mouse model of AD. ME...

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Detalles Bibliográficos
Autores principales: Wang, Jian-Hui, Lei, Xi, Cheng, Xiao-Rui, Zhang, Xiao-Rui, Liu, Gang, Cheng, Jun-Ping, Xu, Yi-Ran, Zeng, Ju, Zhou, Wen-Xia, Zhang, Yong-Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154149/
https://www.ncbi.nlm.nih.gov/pubmed/27964740
http://dx.doi.org/10.1186/s13195-016-0226-6