Cargando…
Non-canonical integration events in Pichia pastoris encountered during standard transformation analysed with genome sequencing
The non-conventional yeast Pichia pastoris is a popular host for recombinant protein production in scientific research and industry. Typically, the expression cassette is integrated into the genome via homologous recombination. Due to unknown integration events, a large clonal variability is often e...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154183/ https://www.ncbi.nlm.nih.gov/pubmed/27958335 http://dx.doi.org/10.1038/srep38952 |