A novel pleuromutilin antibacterial compound, its binding mode and selectivity mechanism

The increasing appearance of pathogenic bacteria with antibiotic resistance is a global threat. Consequently, clinically available potent antibiotics that are active against multidrug resistant pathogens are becoming exceedingly scarce. Ribosomes are a main target for antibiotics, and hence are an o...

Descripción completa

Detalles Bibliográficos
Autores principales: Eyal, Zohar, Matzov, Donna, Krupkin, Miri, Paukner, Susanne, Riedl, Rosemarie, Rozenberg, Haim, Zimmerman, Ella, Bashan, Anat, Yonath, Ada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154188/
https://www.ncbi.nlm.nih.gov/pubmed/27958389
http://dx.doi.org/10.1038/srep39004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154188/
https://www.ncbi.nlm.nih.gov/pubmed/27958389
http://dx.doi.org/10.1038/srep39004

Ejemplares similares