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Inhibition of de novo Methyltransferase 3B is a Potential Therapy for Hepatocellular Carcinoma
BACKGROUND: Aberrant epigenetic patterns, including inactivation of tumor suppressor genes due to DNA methylation, have been described in many human cancers. Epigenetic therapeutic is a new and rapidly developing area of tumor treatment because DNA methyltransferase (DNMT) inhibitors can reverse its...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Elmer Press
2008
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154213/ https://www.ncbi.nlm.nih.gov/pubmed/27994704 http://dx.doi.org/10.4021/gr2008.10.1240 |