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Inhibition of de novo Methyltransferase 3B is a Potential Therapy for Hepatocellular Carcinoma

BACKGROUND: Aberrant epigenetic patterns, including inactivation of tumor suppressor genes due to DNA methylation, have been described in many human cancers. Epigenetic therapeutic is a new and rapidly developing area of tumor treatment because DNA methyltransferase (DNMT) inhibitors can reverse its...

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Detalles Bibliográficos
Autores principales: Fan, Hong, Cheng, Jian, Zhao, Zhu Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elmer Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154213/
https://www.ncbi.nlm.nih.gov/pubmed/27994704
http://dx.doi.org/10.4021/gr2008.10.1240