Dysregulation of Bmi1 promotes malignant transformation of hepatic progenitor cells

Adult hepatic progenitor cells (HPCs) are involved in a wide range of human liver diseases, including hepatocellular carcinoma (HCC). Bmi1 has been reported to have vital roles in stem cell self-renewal and carcinogenesis. We have previously demonstrated that Bmi1 is upregulated in HCC with bile duc...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, R, Wu, W R, Shi, X D, Xu, L B, Zhu, M S, Zeng, H, Liu, C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154353/
https://www.ncbi.nlm.nih.gov/pubmed/26926789
http://dx.doi.org/10.1038/oncsis.2016.6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154353/
https://www.ncbi.nlm.nih.gov/pubmed/26926789
http://dx.doi.org/10.1038/oncsis.2016.6

Ejemplares similares