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Pegylated-asparaginase during induction therapy for adult acute lymphoblastic leukaemia: toxicity data from the UKALL14 trial

Safety and efficacy data on pegylated asparaginase (PEG-ASP) in adult acute lymphoblastic leukaemia (ALL) induction regimens are limited. The UK National Cancer Research Institute UKALL14 trial NCT01085617 prospectively evaluated the tolerability of 1000 IU/m(2) PEG-ASP administered on days 4 and 18...

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Detalles Bibliográficos
Autores principales: Patel, B, Kirkwood, A A, Dey, A, Marks, D I, McMillan, A K, Menne, T F, Micklewright, L, Patrick, P, Purnell, S, Rowntree, C J, Smith, P, Fielding, A K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154375/
https://www.ncbi.nlm.nih.gov/pubmed/27480385
http://dx.doi.org/10.1038/leu.2016.219