Molecular mechanisms underlying Spinocerebellar Ataxia 17 (SCA17) pathogenesis

Spinocerebellar ataxia 17 (SCA17) belongs to the family of 9 genetically inherited, late-onset neurodegenerative diseases, which are caused by polyglutamine (polyQ) expansion in different proteins. In SCA17, the polyQ expansion occurs in the TATA box binding protein (TBP), which functions as a gener...

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Detalles Bibliográficos
Autores principales: Yang, Su, Li, Xiao-Jiang, Li, Shihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Addendum
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154381/
https://www.ncbi.nlm.nih.gov/pubmed/28032013
http://dx.doi.org/10.1080/21675511.2016.1223580

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154381/
https://www.ncbi.nlm.nih.gov/pubmed/28032013
http://dx.doi.org/10.1080/21675511.2016.1223580

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