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Detecting Mutations in the Mycobacterium tuberculosis Pyrazinamidase Gene pncA to Improve Infection Control and Decrease Drug Resistance Rates in Human Immunodeficiency Virus Coinfection

Hospital infection control measures are crucial to tuberculosis (TB) control strategies within settings caring for human immunodeficiency virus (HIV)–positive patients, as these patients are at heightened risk of developing TB. Pyrazinamide (PZA) is a potent drug that effectively sterilizes persiste...

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Detalles Bibliográficos
Autores principales: Dudley, Matthew Z., Sheen, Patricia, Gilman, Robert H., Ticona, Eduardo, Friedland, Jon S., Kirwan, Daniela E., Caviedes, Luz, Rodriguez, Richard, Cabrera, Lilia Z., Coronel, Jorge, Grandjean, Louis, Moore, David A. J., Evans, Carlton A., Huaroto, Luz, Chávez-Pérez, Víctor, Zimic, Mirko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Tropical Medicine and Hygiene 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154434/
https://www.ncbi.nlm.nih.gov/pubmed/27928075
http://dx.doi.org/10.4269/ajtmh.15-0711