Elimination of Latently HIV-infected Cells from Antiretroviral Therapy-suppressed Subjects by Engineered Immune-mobilizing T-cell Receptors

Persistence of human immunodeficiency virus (HIV) in a latent state in long-lived CD4+ T-cells is a major barrier to eradication. Latency-reversing agents that induce direct or immune-mediated cell death upon reactivation of HIV are a possible solution. However, clearance of reactivated cells may re...

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Detalles Bibliográficos
Autores principales: Yang, Hongbing, Buisson, Sandrine, Bossi, Giovanna, Wallace, Zoë, Hancock, Gemma, So, Chun, Ashfield, Rebecca, Vuidepot, Annelise, Mahon, Tara, Molloy, Peter, Oates, Joanne, Paston, Samantha J, Aleksic, Milos, Hassan, Namir J, Jakobsen, Bent K, Dorrell, Lucy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154472/
https://www.ncbi.nlm.nih.gov/pubmed/27401039
http://dx.doi.org/10.1038/mt.2016.114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154472/
https://www.ncbi.nlm.nih.gov/pubmed/27401039
http://dx.doi.org/10.1038/mt.2016.114

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