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An Efficient Microarray-Based Genotyping Platform for the Identification of Drug-Resistance Mutations in Majority and Minority Subpopulations of HIV-1 Quasispecies

The response of human immunodeficiency virus type 1 (HIV-1) quasispecies to antiretroviral therapy is influenced by the ensemble of mutants that composes the evolving population. Low-abundance subpopulations within HIV-1 quasispecies may determine the viral response to the administered drug combinat...

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Detalles Bibliográficos
Autores principales: Martín, Verónica, Perales, Celia, Fernández-Algar, María, Dos Santos, Helena G., Garrido, Patricia, Pernas, María, Parro, Víctor, Moreno, Miguel, García-Pérez, Javier, Alcamí, José, Torán, José Luis, Abia, David, Domingo, Esteban, Briones, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154500/
https://www.ncbi.nlm.nih.gov/pubmed/27959928
http://dx.doi.org/10.1371/journal.pone.0166902