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Unsupervised Cryo-EM Data Clustering through Adaptively Constrained K-Means Algorithm
In single-particle cryo-electron microscopy (cryo-EM), K-means clustering algorithm is widely used in unsupervised 2D classification of projection images of biological macromolecules. 3D ab initio reconstruction requires accurate unsupervised classification in order to separate molecular projections...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154524/ https://www.ncbi.nlm.nih.gov/pubmed/27959895 http://dx.doi.org/10.1371/journal.pone.0167765 |