Cargando…

Photosensitized UVA-Induced Cross-Linking between Human DNA Repair and Replication Proteins and DNA Revealed by Proteomic Analysis

[Image: see text] Long wavelength ultraviolet radiation (UVA, 320–400 nm) interacts with chromophores present in human cells to induce reactive oxygen species (ROS) that damage both DNA and proteins. ROS levels are amplified, and the damaging effects of UVA are exacerbated if the cells are irradiate...

Descripción completa

Detalles Bibliográficos
Autores principales: Guven, Melisa, Barnouin, Karin, Snijders, Ambrosius P., Karran, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2016
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154610/
https://www.ncbi.nlm.nih.gov/pubmed/27654267
http://dx.doi.org/10.1021/acs.jproteome.6b00717