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Postictal behavioural impairments are due to a severe prolonged hypoperfusion/hypoxia event that is COX-2 dependent

Seizures are often followed by sensory, cognitive or motor impairments during the postictal phase that show striking similarity to transient hypoxic/ischemic attacks. Here we show that seizures result in a severe hypoxic attack confined to the postictal period. We measured brain oxygenation in local...

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Detalles Bibliográficos
Autores principales: Farrell, Jordan S, Gaxiola-Valdez, Ismael, Wolff, Marshal D, David, Laurence S, Dika, Haruna I, Geeraert, Bryce L, Rachel Wang, X, Singh, Shaily, Spanswick, Simon C, Dunn, Jeff F, Antle, Michael C, Federico, Paolo, Teskey, G Campbell
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154758/
https://www.ncbi.nlm.nih.gov/pubmed/27874832
http://dx.doi.org/10.7554/eLife.19352