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eIF2α-mediated translational control regulates the persistence of cocaine-induced LTP in midbrain dopamine neurons

Recreational drug use leads to compulsive substance abuse in some individuals. Studies on animal models of drug addiction indicate that persistent long-term potentiation (LTP) of excitatory synaptic transmission onto ventral tegmental area (VTA) dopamine (DA) neurons is a critical component of susta...

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Detalles Bibliográficos
Autores principales: Placzek, Andon N, Prisco, Gonzalo Viana Di, Khatiwada, Sanjeev, Sgritta, Martina, Huang, Wei, Krnjević, Krešimir, Kaufman, Randal J, Dani, John A, Walter, Peter, Costa-Mattioli, Mauro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154759/
https://www.ncbi.nlm.nih.gov/pubmed/27960077
http://dx.doi.org/10.7554/eLife.17517