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STAT1 regulates marginal zone B cell differentiation in response to inflammation and infection with blood-borne bacteria

Marginal zone B (MZ B) cells can rapidly produce antibody in response to infection with blood-borne encapsulated pathogens. Although TLR-mediated activation of MZ B is known to trigger humoral immune response, the signal cascade directing this response remains undefined. Here, we demonstrate that ST...

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Detalles Bibliográficos
Autores principales: Chen, Ting-Ting, Tsai, Ming-Hsun, Kung, John T., Lin, Kuo-I, Decker, Thomas, Lee, Chien-Kuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154933/
https://www.ncbi.nlm.nih.gov/pubmed/27849553
http://dx.doi.org/10.1084/jem.20151620