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Tissue-specific programming of memory CD8 T cell subsets impacts protection against lethal respiratory virus infection

How tissue-specific anatomical distribution and phenotypic specialization are linked to protective efficacy of memory T cells against reinfection is unclear. Here, we show that lung environmental cues program recently recruited central-like memory cells with migratory potentials for their tissue-spe...

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Detalles Bibliográficos
Autores principales: Abboud, Georges, Desai, Pritesh, Dastmalchi, Farhad, Stanfield, Jessica, Tahiliani, Vikas, Hutchinson, Tarun E., Salek-Ardakani, Shahram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154936/
https://www.ncbi.nlm.nih.gov/pubmed/27879287
http://dx.doi.org/10.1084/jem.20160167