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RAB43 facilitates cross-presentation of cell-associated antigens by CD8α(+) dendritic cells

In this study, to examine cross-presentation by classical dendritic cells (DCs; cDCs), we evaluated the role of RAB43, a protein found to be selectively expressed by Batf3-dependent CD8α(+) and CD103(+) compared with other DC subsets and immune lineages. Using a specific monoclonal antibody, we loca...

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Detalles Bibliográficos
Autores principales: Kretzer, Nicole M., Theisen, Derek J., Tussiwand, Roxane, Briseño, Carlos G., Grajales-Reyes, Gary E., Wu, Xiaodi, Durai, Vivek, Albring, Jörn, Bagadia, Prachi, Murphy, Theresa L., Murphy, Kenneth M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154939/
https://www.ncbi.nlm.nih.gov/pubmed/27899443
http://dx.doi.org/10.1084/jem.20160597